RESEARCH PROJECTS

List of research projects 2011-2020, only as Principal Investigator (academics of the cloister).

          2010

  • Oxidative stress in cryopreserved bovine spermatozoa: Effect on gene expresion and quality of embryos produced in vitro. FONDECYT. 2010-2013.

       

          2013

  • Induction and modulation of oxidative stress in bovine embryos at the oocyte stage blastocist Improves rate: expression of genes involved in. The regulation of cell redox. FONDECYT. 2013-2016.

       

          2018

  • Development of a boar semen cryopreservation medium by modulating oxidative/nitrosative stress and neutrophil extracellular traps (nets): Impact on sperm function and reproductive outcome. FONDECYT. 2018-2021.

          2015

  • Identification of novel proteins down-regulated by DNA methylation capable of been reactivated through ATFS: an approach to coadjuvant treatment in drug-resistant gastric cancer. FONDECYT. 2015-2018.

 

          2017

  • Characterization of autophagy induced by oxidative/nitrosative stress in human spermatozoa and its pharmacological enhancement as a strategy for improving cryopreservation outcome. FONDECYT. 2017-2021.

 

          2020

  • The in vitro effect of neutrophil extracellular traps (NETs) on bovine sperm function and its impact in the fertilization outcome. FONDECYT Nº 11200955. 2020-2023.

         2011

  • Detection of hypermethylated genes in cytobrush, serum and urine of women with cervical neoplasia as biomarkers of early diagnosis, progression and/or prognosis. FONDECYT Nº 3120141. 2011-2014.

         2018

  • Bioinformatic approach for understanding cancer and its relationship to cardiovascular diseases: In search of new targets. FONDECYT. 2018-2021.

          2014

  • Bioinformatic approach for understanding cancer and its relationship to cardiovascular diseases: In search of new targets. FONDECYT. 2018-2021.

          2018

  • Bioinformatic approach for understanding cancer and its relationship to cardiovascular diseases: In search of new targets. FONDECYT. 2018-2021.

          2009

  • Design and construction of a methodological quality scale for the evaluation of descriptive observational studies. DIUFRO, Project DI09-0060. 2009-2011.

          2011

  • Differential effect of early and late adverse experiences on stress-induced feeding response in rats: behavioural and neuroanatomical study. DIUFRO N° DI11-0054. 2011-2012.

          2012

  • Design and construction of a methodological quality scale for evaluation of diagnostic test studies. DIUFRO, Project DI12-0037. 2012-2013.

  • Integration of non-vascularized autogenous bone grafts in different installation conditions. Histomorphometric study in rabbit mandible DIUFRO N° DI12-0015. 2012-2014.

  • Histological and stereological study of the wound healing process in guinea pigs (cavia porcellus) treated with ulmo honey + vitamin C and advanced dressings. DIUFRO Nº DI13-0044. 2012-2015.

          2013

  • Detection Kit silent sexually investigación enlos transmitted infections in urine samples. A noninvasivediagnostictool and inexpensive. DIUFRO. 2013- 2016.

          2014

  • Morphometric study of facial asymmetry by facial, photographic, and imaging analysis. DIUFRO N° DI14-0049 2014. 2014-2015.

          2015

  • Study of the macro and microscopic morphology of the glossopharyngeal nerve and its microvascularization, through dissection and slice plastination techniques. DIUFRO. 2015-2017.

  • Generation, construction and validation of a predictive score for the development of postoperative morbidity in patients undergoing surgery for hepatic hydatidosis. DIUFRO. Project DI16-0119. 2015-2018.

          2016

  • Effects of oral administration of beta-carotene on insulin sensitivity and morpho-quantitative characteristics of liver and pancreas in c57bl/6 mice previously exposed to low and moderate dose ethanol consumption. DIUFRO DI16-0132. 2016-2018

  • Analysis of condylar response to partial mandibular condylectomy. Macroscopic and microscopic study in animal model. DIUFRO DI16-0003. 2016-2018.

          2017

  • First experience in fixation of organs and animal bodies with the Walther Thiel technique and subsequent replacement with plastination techniques with silicone and epoxy resin, for their final long-term preservation. Its usefulness in undergraduate anatomy teaching and postgraduate morphology research and clinical/surgical training. DIUFRO. 2017-2019

  • Evaluation of the healing and bactericidal capacity of ulmo honey (eucryphia cordifolia) of different purity grades. DIUFRO. 2017-2019.

  • Factors associated with suicide mortality in children and adolescents in latin america: systematic review of the literature. ASSOCIATIVE RESEARCH PROJECTS FACULTIES (UFRO) 2017-2019.

          2018

  • Study of the NETosis process involved in the entrapment of porcine spermatozoa and its impact on the function and fertilizing capacity Research Directorate, Universidad de La Frontera. DIUFRO INI- DI18-0104. 2018-2019.

  • Morpho-quantitative study of the conformation, vascularization and innervation muscle fibers of the perioral musculature by dissection, histological techniques, traditional and Walther Thiel fixation, and silicone plastination and epoxy resin cutting techniques. Its importance in clinical-surgical practice. UFRO (IAF-PIA). 2018-2021.

          2019

  • Molecular epidemiology of echinococcosis in the region of La Araucanía. Genotypic, morphological and phenotypic evaluation of infection in different hosts. DIUFRO. Project DI18-0040. 2019-2022.

          2020

  • Role of CCL5/CCR5 in the induction of cisplatin-resistant phenotype in gastric cancer cell lines. DIUFRO. 2020-2023.

          2015

  • Determination of tumor markers in ovarian tissue samples in patients of fertility preservation programs. UFRO INNOVA. 2015-2015.

  • Detection and evaluation of Helicobacter pylori resistance genes in saliva. UFRO INNOVA. 2015-2015.

          2016

  • Development of a thermo-responsive hydrogel for alveolar preservation, bone regeneration and prevention of the incidence of post tooth extraction alveolitis. UFRO INNOVA. 2016-2017.

          2017

  • Semen cryopreservation: an alternative to improve production in swine herds. UFRO INNOVA. 2017-2018.

          2013

  • Evaluación de técnicas de multiplicación de Cyttaria espinosae y Grifola gargal y de sus capacidades antioxidantes, anticancerígenas y antimicrobianas frente a patógenos de interés clínico y agrícola. FONDEF IDEA CA12i10134. 2013-2014.

 

          2017

  • Efecto radioprotector de un novedoso sistema inyectable de dosis graduable para la administración de un factor de crecimiento dual contra el daño y deterioro de glándulas salivales tras la irradiación gamma en la región cabeza y cuello. FONDEF. 2017-2019.

          2013

  • Effect of Vitrification on Thiols linked to sperm motility. Short Stays Modality (SCM). 2013-2013.

          2018

  • Malnutrition due to excess and obesity, main determinants of chronic non-communicable pathology. MEC 262621. 2018-2019.

          2020

  • Association between malnutrition by excess and obesity; and hepatobiliary and pancreatic cancers. MEC 80190026. 2020-2022.

          2019

  • Morphologic analysis of mandibular condyle microvascularization by slice plastination techniques and histologic methods for application in the development of autologous temporomandibular joint grafts. STATEWIDE DENTAL NETWORK. 2019-2021.

          2020

  • Análisis morfológico de la microvascularización del cóndilo de mandíbula por medio de técnicas de plastinación de cortes y métodos histológicos para su aplicación en el desarrollo de injertos autólogos de la articulación temporomandibular. RED ESTATAL DE ODONTOLOGÍA. 2019-2021.

          2014

  • UERJ-/UFRO cooperation in human and experimental biology. FAPERJ-BRAZIL-UFRO. 2014-2015.

          2017

  • Strengthening research in Reproductive Medicine at Universidad de La Frontera in sperm cryopreservation. CONICYT/ANID. Program for the Insertion of Advanced Human Capital in Academia 2017-2019.

          2019

  • Genetic and proteomic characteristics of Echinococcus granulosus. Association with different hosts. CONACYT-CINVESTAV No. 382646, Mexico. 2019-2021.

          2016

  • Analysis of Facial Morphology in Subjects with Facial Deformities Candidates for Orthographic / Orthofacial Surgery. UNETE RESEARCH FUND (UFRO). 2016-2018.

 

          2018

  • Morpho-quantitative study of the conformation, vascularization and innervation muscle fibers of the perioral musculature by dissection, histological techniques, traditional and Walther Thiel fixation, and silicone plastination techniques. UFRO PROJECTS FOR ASSOCIATIVE RESEARCH FACULTIES. 2018-2020.

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